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picture1_Journal Pdf 97511 | Abstract Guidelines Nature Journal Qip46l


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File: Journal Pdf 97511 | Abstract Guidelines Nature Journal Qip46l
summary abstract writing nature is a top ranking journal in the natural sciences the editorial staff recommend submitted abstracts follow this structure a summary separate from the main text of ...

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                      Summary/abstract writing 
                  Nature is a top ranking journal in the natural sciences. The editorial staff 
                  recommend submitted abstracts follow this structure: 
                      …a summary, separate from the main text, of up to 150 words, which does not have 
                      references, and does not contain numbers, abbreviations, acronyms or 
                      measurements unless essential. It is aimed at readers outside the discipline. This 
                      summary contains a paragraph (2-3 sentences) of basic-level introduction to the 
                      field; a brief account of the background and rationale of the work; a statement of the 
                      main conclusions (introduced by the phrase 'Here we show' or its equivalent); and 
                      finally, 2-3 sentences putting the main findings into general context so it is clear 
                      how the results described in the paper have moved the field forwards.  
                      Source: www.nature.com/nature/authors/gta   
                      How to construct a Nature summary paragraph 
                      basic introduction to the field, 
                      comprehensible to a scientist in                      During cell division, mitotic spindles are assembled by 
                      any discipline (1-2                                                                         1, 2
                      sentences).                                           microtubule-based motor proteins         . The bipolar organization 
                                                                            of spindles is essential for proper segregation of chromosomes, 
                                                                            and requires plus-end-directed homotetrameric motor proteins 
                      more detailed                                                                                              3
                                                                            of the widely conserved kinesin-5 (BimC) family . Hypotheses 
                      background, comprehensible to                         for bipolar spindle formation include the 'push−pull mitotic 
                      scientists in related disciplines (2-3                muscle' model, in which kinesin-5 and opposing motor proteins 
                      sentences)                                                                                      2, 4, 5
                                                                            act between overlapping microtubules           .  However, the 
                                                                            precise roles of kinesin-5 during this process are unknown.  
                      general problem being                                 Here we show that the vertebrate kinesin-5 Eg5 drives the 
                      addressed by this particular study(1                  sliding of microtubules depending on their relative orientation.  
                      sentence)                                             We found in controlled in vitro assays that Eg5 has the 
                                                                                                                                                -1
                                                                            remarkable capability of simultaneously moving at  20 nm s  
                      summary of main result (with                          towards the plus-ends of each of the two microtubules it 
                      the words “here we show” or their                     crosslinks. For anti-parallel microtubules, this results in 
                      equivalent, in 1 sentence)                                                          -1
                                                                            relative sliding at   40 nm s , comparable to spindle pole 
                                                                                                      6
                                                                            separation rates in vivo . Furthermore, we found that Eg5 can 
                      what the main result reveals in                       tether microtubule plus-ends, suggesting an additional 
                      direct comparison to what was                         microtubule-binding mode for Eg5.  Our results demonstrate 
                      thought to be the case previously, or how             how members of the kinesin-5 family are likely to function in 
                      the main result adds to previous                      mitosis, pushing apart interpolar microtubules as well as 
                      knowledge (2-3 sentences)                             recruiting microtubules into bundles that are subsequently 
                                                                            polarized by relative sliding.  We anticipate our assay to be a 
                      results put into more general                         starting point for more sophisticated in vitro models of mitotic 
                      context (1-2 sentences)                               spindles. For example, the individual and combined action of 
                                                                            multiple mitotic motors could be tested, including minus-end-
                      broader perspective, readily                          directed motors opposing Eg5 motility. Furthermore, Eg5 
                      comprehensible to a scientist in                      inhibition is a major target of anti-cancer drug development, 
                      any discipline, may be included if                    and a well-defined and quantitative assay for motor function 
                      the editor considers that the                         will be relevant for such developments.  
                      accessibility of the paper is significantly 
                      enhanced by their inclusion. (2-3                      
                      sentences. Under these circumstances, the length of the paragraph can be up to 300 words. 
                      The above example is 190 words without the final section, and 250 words with it. 
                
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...Summary abstract writing nature is a top ranking journal in the natural sciences editorial staff recommend submitted abstracts follow this structure separate from main text of up to words which does not have references and contain numbers abbreviations acronyms or measurements unless essential it aimed at readers outside discipline contains paragraph sentences basic level introduction field brief account background rationale work statement conclusions introduced by phrase here we show its equivalent finally putting findings into general context so clear how results described paper moved forwards source www com authors gta construct comprehensible scientist during cell division mitotic spindles are assembled any microtubule based motor proteins bipolar organization for proper segregation chromosomes requires plus end directed homotetrameric more detailed widely conserved kinesin bimc family hypotheses spindle formation include push pull scientists related disciplines muscle model opposi...

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