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picture1_Neph   Nephrotic Syndrome Fact Sheet   Get The Facts On Nephrotic Syndrome


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File: Neph Nephrotic Syndrome Fact Sheet Get The Facts On Nephrotic Syndrome
3 out of incidence rate of new cases of nephrotic syndrome in the united states is 3 out of 100 000 1 get the facts on every 100 000 people ...

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            3 out of       Incidence (rate of new cases) of nephrotic 
                           syndrome in the United States is 3 out of  
            100,000                                         1                     Get the Facts on  
                           every 100,000 people each year.                        Nephrotic Syndrome 
                                                                                  Nephrotic syndrome is a group of symptoms that indicate 
                                                                                  that the kidneys are damaged. The kidneys’ filters 
                                                                                  (glomeruli) remove waste from the blood and allow blood to 
                                                                                  keep the things that the body needs, like cells and proteins. 
                                                                                  When the kidneys are damaged, they can’t filter the protein 
                                                                                  in the blood properly and protein ends up in the urine.2
                 Signs and Symptoms of Nephrotic Syndrome 
                 Signs and symptoms of nephrotic syndrome will vary for each person. Listed below are some common 
                                                                       2
                 signs and symptoms individuals report.
                                 FATIGUE  
                                 (FEELING TIRED)                                                                                         EDEMA 
                                                                                                                                         (SWELLING) 
                                                                                                                                         In the legs,  
                                                                                                                                         feet, or ankles 
                                 WEIGHT GAIN 
                                                                                                                                        FOAMY URINE
                               LOSS OF                                                                                                  Due to extra 
                               APPETITE                                                                                                 protein in urine 
                 Causes of Nephrotic Syndrome
                 Many diseases and conditions can cause damage to the kidneys. These may be                                                   Our greatest weakness 
                 diseases and conditions that only affect the kidneys (called primary causes of                                               lies in giving up. The 
                 nephrotic syndrome) or many parts of the body (called secondary causes of                                                    most certain way to 
                                              2                                                                                               succeed is always to try 
                 nephrotic syndrome).  Some diseases that can cause nephrotic syndrome include:                                               just one more time.
                                                                                                                                              Thomas Edison
                 Focal segmental glomerulosclerosis                     Immunoglobulin A (IgA) nephropathy
                 (FSGS)3                                                IgA nephropathy is a disorder involving 
                 FSGS is a condition involving scar tissue              the immune system where IgA antibodies 
                 developing in the filters (glomeruli) of               are deposited and become trapped in the 
                 the kidneys. The exact cause of FSGS                   glomeruli of the kidneys.4 The exact cause of 
                 is unknown; however, genetic and                       IgA nephropathy is unknown; however, it is 
                 environmental factors may be involved.                 thought to be linked to genetic factors.5
                                                                         
                 Other diseases that can cause nephrotic syndrome include: Minimal change disorder, 
                 membranous nephropathy, and lupus.1
                 References: 1. Nephrotic Syndrome. NephCure Kidney International website. https://nephcure.org/livingwithkidneydisease/understanding-
                 glomerular-disease/understanding-nephrotic-syndrome/. Accessed April 22, 2020. 2. Nephrotic Syndrome in Adults. National Institute of Diabetes 
                 and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/kidney-disease/nephrotic-syndrome-adults. Accessed March 18, 
                 2020. 3. Focal Segmental Glomerulosclerosis. NephCure. https://nephcure.app.box.com/s/rc98yosh958s00ea0g44d1pul8iesz9a. Accessed April 20, 
                                                                                                                           
                 2020. 4. IgA Nephropathy. NIDDK. https://www.niddk.nih.gov/health-information/kidney-disease/iga-nephropathy. Accessed March 18, 2020. 
                 5. Satpathy HK. IgA Nephropathy. In: Ferri FF, ed. Ferri’s Clinical Advisor 2013. 1st ed. St. Louis: Mosby; 2012: 570-571. 
                              Please see the other side of this handout for information on nephrotic syndrome resources.
         Get the Facts on Nephrotic Syndrome
                                                                     Treating Nephrotic Syndrome
                                                                     Doctor(s) may treat the condition that is causing the 
                                                                     nephrotic syndrome. Medications and changes in your 
                                                                     diet may be suggested to manage symptoms and treat 
                                                                                   2
                                                                     complications.  
                                                                     Treatment for nephrotic syndrome is different for every 
                                                                     person. Individuals should talk to their doctor(s) to 
                                                                     determine which treatment(s) may be right for them!
                                                                     Treatments may include: 
                                                                          Medications 
                                                                          Changes in diet
             Goals of Nephrotic Syndrome                                                                       It does not matter how 
             Treatment                                                                                         slowly you go so long 
                                                                                                               as you do not stop.
             It is important to understand the goals of your                                                   Confucius
             individualized nephrotic syndrome treatment plan. 
             Identifying and keeping track of treatment goals 
             is a key first step. Individuals should discuss their 
             treatment goals with their doctor. Some nephrotic 
                                           2
             treatment goals may include:  
                   Treating complications of nephrotic syndrome
                   Managing  symptoms
             Self-Care and Nephrotic Syndrome 
             Coping with nephrotic syndrome can be overwhelming at times and therefore, staying positive is important. 
             Practicing proper self-care can help and is important for both your mental and physical well-being. Some ideas 
                                       6
             for self-care may include:
                 Staying connected with friends/family                     Investing in a hobby
                 Engaging in activities you enjoy                          Seeking quiet through meditation and/or prayer
                 Seeking humorous and upbeat entertainment                 Eating healthy meals 
                 Setting aside leisure time (eg, reading a book,           Working with your healthcare provider to develop  
                watching TV, listening to a podcast)                      an exercise program that’s right for you
             More Information, Support, and Educational Resources
             This list includes helpful websites and organizations that provide information about nephrotic syndrome, 
             support groups, and other resources! 
                 NephCure  Kidney                National  Kidney                 American Association of 
                International                   Foundation                      Kidney Patients  
                www.nephcure.org                www.kidney.org                  www.aakp.org                          NS
                  American Kidney Fund            Renal Support Network           National Alliance for 
                www.kidneyfund.org              www.rsnhope.org                 Caregiving  
                                                                                www.caregiving.org
             References: 6. Self-Care for Autoimmune Disease Patients. American Autoimmune website. https://www.aarda.org/self-care/. Published September, 2018. Accessed March 5, 2020.
             This informational sheet may identify third-party organizations and provide links to third- party websites or other third-party information (third-party content). The third-party content is 
             meant for informational purposes only, is not endorsed by or under the control of Mallinckrodt, and is not meant to replace a physician’s medical advice. Mallinckrodt has no responsibility 
             or liability for and makes no representations or warranties whatsoever about any third-party content. All trademarks, service marks and logos appearing on this page are the property of 
             their respective owners. Any rights not expressly granted herein are reserved.
     Mallinckrodt, the “M” brand mark and the Mallinckrodt Pharmaceuticals logo are trademarks of a Mallinckrodt company. © 2020 Mallinckrodt. US-2001095 07/20. 
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