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picture1_Specs Tissue Chip Validation


 151x       Filetype XLSX       File size 0.02 MB       Source: ncats.nih.gov


File: Specs Tissue Chip Validation
column1 column2 column3 column4 pi organ system cell source ec matrix christiano skin ipsc some primary collagen fibrin laminin donowitz gi primary collagen iv s george microvascularendothelial ok stromal cells ...

icon picture XLSX Filetype Excel XLSX | Posted on 31 Jul 2022 | 3 years ago
Partial file snippet.
            Column1       Column2                         Column3                     Column4
            PI            Organ System                    Cell Source                 EC Matrix 
            Christiano    Skin                            iPSC, some primary          Collagen, fibrin, laminin
            Donowitz      GI                              primary                     collagen IV
            S. George     microvascular-endothelial       OK                          Stromal cells; collagen or 
                                                                                      fibrinogen matrix
            S. George     tumor                           cell line and some primary  Stromal cells; collagen or 
                                                                                      fibrinogen matrix
            S. George     heart-cardiomyocytes            iPSC and some primary       Stromal cells; collagen or 
                                                                                      fibrinogen matrix
                              liver-hepatocytes plus 
                              nonparenchymal cells                                                Hydrogel with stromal 
             Griffith         (endothelial cells, Kupffer cells, primary and iPSC                 cells; matrix self-organized
                              stellate cells, fibroblasts and 
                              immune cells)
                              tumor-breast cancer 
             Griffith         metastasis in liver (can be any  primary and cell lines             Hydrogel with stromal 
                              tumor type - have used breast,                                      cells; matrix self-organized
                              prostate, and melanoma)
             Healy            microvascular-endothelial cells iPSC                                GFR-Matrigel; 0.2% Gelatin
             Healy            liver-hepatocytes                   iPSC                            GFR-Matrigel
             Healy            heart-cardiomyocytes                iPSC                            small precent stromal cells
             Healy            fat-white, adipocytes               cell line                       Hyaluronic acid hydrogel
                                                                  healthy iPSCs                   fibrin 
             Vunjak-Nova heart-cardiomyocytes                     patients' iPSCs                 native tissue ECM
                                                                  supporting non-myocytes
             Vunjak-Nova liver-hepatocytes                       iPSC; cell lines; reporters     stromal-fibroblasts  
             Vunjak-Nova bone - tumor                            iPSCs                           hydrogels
                                                                 cancer cells                    native tissue ECM
             Vunjak-Nova microvascular-endothelial               iPSC                            stromal cells, collagen, 
                                                                                                 fibrin, or matrigel
             Himmelfarb       kidney-proximal tubule,            Mostly primary, some iPSC
           Himmelfarb     kidney-derived microvascular  Mostly primary, some iPSC   pericytes
                                                                                    (i) Fibronectin                      
                                                                                    (ii) Gelatin                               
           Parker         cardiomyocytes, HUVEC         iPSC, cell lines                 (iii) Laminin                        
                                                                                                 (iv) Collagen               
                                                                                                 (v) Combinations 
                                                                                    thereof
           Taylor         liver-hepatocytes, endothelial,  primary, iPSC            Collagen type 1
                          Kupfer, Stellate
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...Column pi organ system cell source ec matrix christiano skin ipsc some primary collagen fibrin laminin donowitz gi iv s george microvascularendothelial ok stromal cells or fibrinogen tumor line and heartcardiomyocytes liverhepatocytes plus nonparenchymal hydrogel with griffith endothelial kupffer selforganized stellate fibroblasts immune tumorbreast cancer metastasis in liver can be any lines type have used breast prostate melanoma healy gfrmatrigel gelatin small precent fatwhite adipocytes hyaluronic acid healthy ipscs vunjaknova patients native tissue ecm supporting nonmyocytes reporters stromalfibroblasts bone hydrogels matrigel himmelfarb kidneyproximal tubule mostly kidneyderived microvascular pericytes i fibronectin ii parker cardiomyocytes huvec iii v combinations thereof taylor kupfer...

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