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2yrs Mpharm

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                                 EM 4, Sector V, Salt Lake, Kolkata-700091, West Bengal, India 
                                    Phone: +91 9836544416/17/18/19, Fax: +91 33 2357 1097 
                                                                 
                               2-Year Master of Pharmacy (M.Pharm.) Pharmaceutics 
                                                Curriculum and Syllabus 
                                                                
                                                        Semester - I 
               Subject Code              Name of Subject              Credit    Credit points    Hrs./     Marks 
                                                                      Hours                      Wk. 
            TIU-MPH-101T         Modern Pharmaceutical Analytical   4           4               4         100 
                                 Techniques 
            TIU-MPH-102T         Drug Delivery System               4           4               4         100 
            TIU-MPH-103T         Modern Pharmaceutics               4           4               4         100 
            TIU-MPH-104T         Regulatory Affair                  4           4               4         100 
            TIU-MPH-105P         Pharmaceutics Practical I          12          6               12        150 
                                 Seminar/Assignment                 7           4               7         100 
                                 Total                              35          26              35        650 
                                                                
                                                                
                                                       Semester - II 
               Subject Code              Name of Subject              Credit    Credit points    Hrs./     Marks 
                                                                      Hours                      Wk. 
            TIU-MPH-201T         Molecular Pharmaceutics(Nano       4           4               4         100 
                                 Tech and Targeted DDS) 
            TIU-MPH-202T         Advanced Biopharmaceutics &        4           4               4         100 
                                 Pharmacokinetics 
            TIU-MPH-203T         Computer Aided Drug Delivery       4           4               4         100 
                                 System 
            TIU-MPH-204T         Cosmetic and Cosmeceuticals        4           4               4         100 
            TIU-MPH-205P         Pharmaceutics Practical II         12          6               12        150 
               -                 Seminar/Assignment                 7           4               7         100 
                                 Total                              35          26              35        650 
                                                                
                                           
                                   EM - 4, Sector – V, Salt Lake, Kolkata -700091, India 
             
             
             
                                EM 4, Sector V, Salt Lake, Kolkata-700091, West Bengal, India 
                                   Phone: +91 9836544416/17/18/19, Fax: +91 33 2357 1097 
                                                                
                                                       Semester - III 
               Subject Code                           Name of Subject                         Credit      Credit 
                                                                                               Hours       points 
            TIU- MPH-301T         Research Methodology and Biostatistics*                    4           4 
                     -            Journal club                                               1           1 
                     -            Discussion / Presentation (Proposal Presentation)          2           2 
                     -            Research Work                                              28          14 
                                  Total                                                      35          21 
            *Non University Exam 
                                                               
                                                      Semester - IV 
               Subject Code                           Name of Subject                         Credit      Credit 
                                                                                               Hours       points 
                     -            Journal club                                               1           1 
                     -            Discussion / Presentation (Proposal Presentation)          3           3 
                     -            Research Work                                              31          16 
                                  Total                                                      35          20 
                                                               
                                          Semester wise credits distribution 
                                                               
                                            Semester                                  Credit Points 
                                                  I                                          26 
                                                 II                                          26 
                                                 III                                         21 
                                                 IV                                          20 
                      Co-curricular Activities (Attending  Conference,   Scientific     Minimum=02 
                             Presentations  and Other Scholarly Activities)            Maximum=07* 
                                         Total Credit Points                            Minimum=95 
                                                                                      Maximum=100* 
            *Credit Points for Co-curricular Activities 
             
             
              Approved By: 
             
             
             
             External Expert        Vice-Chancellor            Registrar               Director, School  
                                                                                       of Pharmacy 
                                                                                              
                                   EM - 4, Sector – V, Salt Lake, Kolkata -700091, India 
                  
                  
                  
                                               EM 4, Sector V, Salt Lake, Kolkata-700091, West Bengal, India 
                                                   Phone: +91 9836544416/17/18/19, Fax: +91 33 2357 1097 
                                                                                             
                                                                        SEMESTER - I 
                                       MODERN PHARMACEUTICAL ANALYTICAL TECHNIQUES 
                                                                              (TIU-MPH-101T) 
                 Scope 
                 This  subject  deals  with  various  advanced  analytical  instrumental  techniques  for  identification, 
                 characterization and quantification of drugs. Instruments dealt are NMR, Mass spectrometer, IR, 
                 HPLC, GC etc. 
                 Objectives 
                 After completion of course student is able to know, 
                           Chemicals and Excipients 
                           The analysis of various drugs in single and combination dosage forms 
                           Theoretical and practical skills of the instruments 
                 THEORY                                                                                                                          60 HOURS 
                 1.  a.  UV-Visible spectroscopy: Introduction, Theory, Laws, Instrumentation associated with UV-
                 Visible  spectroscopy,  Choice  of  solvents  and  solvent  effect  and  Applications  of  UV  Visible 
                 spectroscopy. 
                 b. IR spectroscopy: Theory, Modes of Molecular vibrations, Sample handling, Instrumentation of 
                 Dispersive and Fourier -Transform IR Spectrometer, Factors affecting vibrational frequencies and 
                 Applications of IR spectroscopy 
                 c.  Spectroflourimetry:  Theory  of  Fluorescence,  Factors  affecting  fluorescence,  Quenchers, 
                 Instrumentation and Applications of fluorescence spectrophotometer. 
                 d.  Flame  emission spectroscopy and Atomic absorption spectroscopy: Principle, Instrumentation, 
                 Interferences and Applications.                                                                                                              11 Hrs 
                 2  NMR spectroscopy: Quantum numbers and their role in NMR, Principle, Instrumentation, Solvent 
                 requirement  in  NMR,  Relaxation  process,  NMR  signals  in  various  compounds,  Chemical  shift, 
                 Factors influencing chemical shift, Spin-Spin coupling, Coupling constant, Nuclear magnetic double 
                 resonance,  Brief  outline  of  principles  of  FT-NMR  and  13C  NMR.  Applications  of  NMR 
                 spectroscopy.                                                                                                                             11 Hrs 
                 3 Mass Spectroscopy: Principle, Theory, Instrumentation of Mass Spectroscopy, Different types of 
                 ionization like electron impact, chemical, field, FAB and MALDI, APCI, ESI, APPI Analyzers of 
                                                   EM - 4, Sector – V, Salt Lake, Kolkata -700091, India 
                    
                    
                    
                                                   EM 4, Sector V, Salt Lake, Kolkata-700091, West Bengal, India 
                                                        Phone: +91 9836544416/17/18/19, Fax: +91 33 2357 1097 
                                                                                                     
                   Quadrupole and Time of Flight, Mass fragmentation and its rules, Meta stable ions, Isotopic peaks 
                   and Applications of Mass spectroscopy                                                                                                                11Hrs 
                   4  Chromatography:  Principle,  apparatus,  instrumentation,  chromatographic  parameters,  factors 
                   affecting resolution and applications of the following: 
                   a) Paper chromatography b) Thin Layer chromatography c) Ion exchange chromatography  
                   d) Column chromatography e) Gas chromatography f) High Performance Liquid chromatography g) 
                   Affinity chromatography                                                                                                                                 11Hrs 
                   5 a. Electrophoresis: Principle, Instrumentation, Working conditions, factors affecting separation and 
                   applications of the following:  
                   a) Paper electrophoresis b) Gel electrophoresis c) Capillary electrophoresis d) Zone electrophoresis 
                   e) Moving boundary electrophoresis f) Isoelectric focusing  
                   b. X ray Crystallography: Production of X rays, Different X ray diffraction methods, Bragg‘s law, 
                   Rotating crystal technique, X ray powder technique, Types of crystals and applications of Xray 
                   diffraction.                                                                                                                                          11Hrs 
                   6 Immunological assays : RIA (Radio immuno assay), ELISA, Bioluminescence assays.          05 Hrs 
                    
                   REFERENCES 
                   1. Spectrometric Identification of Organic compounds - Robert M Silverstein, Sixth edition, John 
                   Wiley & Sons, 2004. 
                   2. Principles of Instrumental Analysis - Doglas A Skoog, F. James Holler, Timothy A. Nieman, 5th 
                   edition, Eastern press, Bangalore, 1998. 
                   3. Instrumental methods of analysis – Willards, 7th edition, CBS publishers. 
                                                                                                                                          th
                   4. Practical Pharmaceutical Chemistry – Beckett and Stenlake, Vol II, 4  edition, CBS Publishers, 
                   New Delhi, 1997. 
                   5. Organic Spectroscopy - William Kemp, 3rd edition, ELBS, 1991. 
                   6.  Quantitative  Analysis  of  Drugs  in  Pharmaceutical  formulation  -  P  D  Sethi,  3rd  Edition,  CBS 
                   Publishers, New Delhi, 1997. 
                   7. Pharmaceutical Analysis- Modern methods – Part B - J W Munson, Volume 11, Marcel Dekker 
                   Series 
                                                                    
                                                       EM - 4, Sector – V, Salt Lake, Kolkata -700091, India 
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...Em sector v salt lake kolkata west bengal india phone fax year master of pharmacy m pharm pharmaceutics curriculum and syllabus semester i subject code name credit points hrs marks hours wk tiu mph t modern pharmaceutical analytical techniques drug delivery system regulatory affair p practical seminar assignment total ii molecular nano tech targeted dds advanced biopharmaceutics pharmacokinetics computer aided cosmetic cosmeceuticals iii research methodology biostatistics journal club discussion presentation proposal work non university exam iv wise credits distribution co curricular activities attending conference scientific minimum presentations other scholarly maximum for approved by external expert vice chancellor registrar director school scope this deals with various instrumental identification characterization quantification drugs instruments dealt are nmr mass spectrometer ir hplc gc etc objectives after completion course student is able to know chemicals excipients the analysi...

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